Accutane Side Effects Can Affect Brain
Elise Kramer | March 22nd, 2012
Although most of the Accutane lawsuits that are currently making their way through the litigation process involve inflammatory bowel disease, other side effects remain a concern, namely Accutane psychological side effects. As early as 1998 drug maker Hoffman-La Roche acknowledged that psychological side effects could be a serious complication related to the acne medication. The Food and Drug Administration placed a warning on Accutane in 1999 concerning psychological side effects, and many studies have been conducted to determine the effects of Accutane on the brain.
Psychological side effects tend to receive less attention in favor of more common allegations of takers developing inflammatory bowel disease after Accutane use. However, sufferers of psychological complications have also reached out to Accutane lawyers.
Accutane suicide a serious concern
Over 5,000 reports of psychiatric disturbances and related side effects came into the agency between the drug’s initial approval, which took place in 1982, and 2004. Nearly 200 Accutane patients committed suicide in the United States through January 2005, although the actual number could be much higher in cases where the suicide was not reported or was not reported as an Accutane side effect. A study in The American Journal of Psychiatry suggested that treatment with Accutane could actually initiate changes in brain functioning, and could actually decrease the brain metabolism in the orbitofrontal cortex by 21 percent. This region of the brain is associated with decision making and cognitive processing.
Victims and family members consider Accutane lawsuits
Researchers who conducted animal studies surrounding the drug found in 2007 that isotretinoin, or Accutane, actually decreased the levels of feel-good chemical serotonin in the brain. A lack of serotonin or a deficit of it has been associated with depression-related behaviors.
Accutane as a brand name product was pulled from the market in 2009 amid a growing number of lawsuits, but generic forms of the drug are still available today.
- Study Results Inconclusive on Whether Accutane Causes Suicide
- Accutane Side Effects: Inflammatory Bowel Disease
- Accutane Linked to Eye-Related Side Effects